Searching EBM sources Filtering Bibliographica Canadiana Types of 'evidence'

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What are the MeSH tree structures?
The hierarchical 'branch-like' structure in Medline presents the thesaurus by breaking it down into more specific topics

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What is the Cochrane Library?
Six high-quality databases health professionals use to synthesize the literature without having to read every study (UBC Library buys 'Ovid EBMR' but it is also available from Wiley publishers)

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What is keyword (also 'natural language' or 'freetext') searching?
In literature searching, the use of everyday natural words and phrases, instead of index terms, to search bibliographic databases

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This Canadian government website lists those drugs approved for use in Canada including their 'drug monographs' (giving an overview of their testing on humans) for free viewing

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This pyramid has RCTs and systematic reviews at the top followed below by lower levels of evidence such as cohort & case controlled studies and called the [blank] of evidence

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What is the scope note?
This part of the MeSH record provides definitions for terms and date when MeSH was created, its entry terms and list of synonyms

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The study includes treatment and comparison groups and participants are randomly assigned to each; an intervention is given and groups are observed. Outcomes such as improvement or harms are noted. These studies are considered the most reliable type of clinical study

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What is truncation or 'wildcard' searching?
This is the name for a search when * $ : or ? are used within words or phrases to search for variants (it is also a way to improve recall in a search)

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This Canadian health librarian working at the McMaster University in the filters unit called HIRU is among the most-cited librarians in Medline

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What is Clinical Evidence (BMJ)?
The British Medical Journal (BMJ) publishes a synopsis of medical evidence (requiring a subscription) and rates each intervention as:
  • Beneficial
  • Likely to be beneficial
  • Unknown effectiveness
  • Likely to be ineffective
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    In PubMed, this is where you can restrict search to major descriptors and check off the box "Do Not Explode" (i.e., do not include MeSH terms below this term in the MeSH tree).

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    What are Medline & Embase?
    For reviews of health care interventions or treatments, these two databases are most commonly used first to identify studies

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    Medline is an 'unfiltered' source even though it has some filtered sources of medical evidence
    Medline contains primary research (original research) and articles that synthesize that research (filtered) making it 'what kind of source'

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    The five top medical journals are BMJ, Lancet, JAMA and the New Eng J of Medicine and this fifth Canadian journal title that goes back to 1911

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    What is UpToDate?
    This popular database requires a subscription and is viewed by health librarians as overpriced ...though clinicians in internal medicine areas often ask for it

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    What are Boolean operators (see George Boole)?
    These are used in all searches with two sets ...& include “AND” “OR” and “NOT” (and are named after a famous English mathematician).

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    What is McMaster University?
    This Canadian university is widely seen as the birthplace of evidence-based medicine due to the work of Gordon Guyatt and David Sackett among others.

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    What are search filters or hedges?
    These predefined strategies improve recall in a search (and are highly sensitive in retrieving 'all relevant articles')

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    These filters, named after the Canadian researcher who tests them, are used in PubMed's clinical queries feature

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    What is SumSearch and the TRIP Database?
    These two metasearch tools have been created to search across several sources of evidence all at once

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    What is Patient (population), Intervention, Comparison and Outcome?
    Constructing an effective combination of search terms involves breaking down the question into ‘concepts’ and keywords. P-I-C-O can help to structure the search (but it is not essential that every element is used) and stands for - what?

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    What is First Consult?
    This evidence-based clinical information tool synthesizes findings from journals and other EBM sources into a templated knowledge base. It offers tools for differential diagnosis, evaluation and management of conditions, patient education - and integrates with MD Consult

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    ...the name for qualifiers in MeSH that increase precision... all 83 of them 'float' among 24,000+ MeSH

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    What is the grey literature?
    When a Canadian study is not published in one of the major biomedical indexes but useful to Canadian physicians it is said to be "this type of literature"

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    These reviews of the literature aim for the highest recall ....and require reproducible searches and detailed documentation

    LIBR534 - Searching in biomedicine, Part I

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